Chloroform CHCl3

Chloroform CHCl3

Chloroform

Product Specification

Chloroform

CHCl3

119.38 g mol1

Colorless liquid

1.483 g/cm3

-63.5 C, 210 K, -82 F

61.2 C, 334 K, 142 F

0.8 g/100 mL (20C)

21.0861 kPa (20C)

1.4459



Versatile Industrial and Laboratory Applications

Chloroform is prominently used as a solvent in laboratories, pharmaceutical formulations, and chemical manufacturing. Its chemical stability and ability to dissolve wide-ranging organic compounds make it essential in research, synthesis, and even in sample preparation. Its role as a precursor in anesthetics and its use for extraction complement its versatility across multiple sectors.


Strict Handling and Safety Measures Required

Due to its toxic and hazardous nature, handling chloroform demands stringent safety protocols. Appropriate personal protective equipment, proper ventilation, and adherence to recommended storage away from light are crucial. Packaging in secure drums or bottles ensures stability and safety during transportation, corresponding to regulatory standards including a UN Number (UN 1888) and hazard statements (H302, H315, H319, H331, H351, H373).


Physical and Chemical Characteristics

Chloroform features a high purity (99% min), a density of 1.48 g/cm, and a refractive index of 1.445 (n20/D). It is a clear, nonflammable liquid at room temperature with a neutral pH. Its characteristic sweet, burning taste and potent ether-like smell are notable identifiers in quality control and handling assessments.

FAQs of Chloroform CHCl3:


Q: How should chloroform (CHCl3) be safely stored and transported?

A: Chloroform should be stored in a cool, well-ventilated area, away from direct light, to ensure stability and minimize decomposition. For transportation, it is typically packaged in galvanized steel drums or glass bottles, complying with international safety and regulatory guidelines such as those associated with UN 1888.

Q: What are the main uses and benefits of chloroform in industry and laboratories?

A: Chloroform is valued mainly for its role as a solvent, capable of dissolving a broad spectrum of organic compounds. It is essential in laboratories for sample preparation, in the pharmaceutical industry for formulations, and in chemical synthesis as a reactant or precursorparticularly in the production of anesthetics and certain refrigerants.

Q: When is special precaution necessary during the handling of chloroform?

A: Special precautions are always required when handling chloroform due to its toxicity and potential health hazards (as indicated by hazard statements H302, H315, H319, H331, H351, H373). Wearing protective gear, using fume hoods, and preventing skin or inhalation exposure are vital safety practices during all stages of handling.

Q: What process is typically followed for using chloroform as a solvent in laboratories?

A: In laboratories, chloroform is used by adding it to reaction or extraction mixtures within sealed systems or under fume hoods to minimize vapor exposure. Because it is slightly soluble in water but miscible with many organic solvents, it is ideal for separating chemical components by liquid-liquid extraction.

Q: Where is chloroform commonly sourced or supplied from in India?

A: Chloroform is distributed, manufactured, and supplied across India by chemical distributors, manufacturers, and traders. Reliable suppliers ensure the product meets ACS/ISO standards, with proper labeling, packaging, and documentation for analytical and industrial grade chloroform.

Q: What is the benefit of using chloroform with a high purity level?

A: Using chloroform with a high purity (99% minimum) is crucial for accurate results in analytical applications, consistency in pharmaceutical processes, and for minimizing impurities in sensitive chemical syntheses. High purity also supports compliance with international standards for laboratory and industrial uses.